Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
CAS No. 2376990-30-4
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride ( —— )
Catalog No. M27021 CAS No. 2376990-30-4
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 63 | Get Quote |
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10MG | 88 | Get Quote |
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25MG | 155 | Get Quote |
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50MG | 264 | Get Quote |
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100MG | 444 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameThalidomide-O-amido-PEG2-C2-NH2 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker.
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DescriptionThalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker. Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride can be used as an immunomodulator for the treatment of cancer.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2376990-30-4
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Formula Weight498.9
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Molecular FormulaC21H27ClN4O8
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.NCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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FIDAS-5
FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding.?FIDAS-5 has anticancer activities.?FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM.FIDAS-5 induces the expression of cell cycle inhibitor, p21WAF1/CIP1. FIDAS-5 (3 μM; 36 h) treatment reduces the levels of both S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in LS174T cells.FIDAS-5 (3 μM; 7 days; LS174T cells) treatment significantly inhibits the proliferation of LS174T cells.
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3-Geranyl-3-prenyl-2...
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone is a natural product from Morus alba.
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8-Epiloganin
The fruits of Cornus officinalis Sieb. et Zucc.